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  INDEPENDENT
  LABORATORY
 100%
dedicated to the assessment of
ENDOCRINE DISRUPTORS
Science

Science

A research team (PhDs in Biology) specialized in elucidating endocrine disruption mechanisms :

  • Estrogens
  • Androgens
  • Thyroid hormones
  • Steroidogenesis
Ethics

Ethics

Alternative methods to replace the use of laboratory animals:

  • Compliant with cosmetic regulation
  • Since 2013 European Cosmetic Regulation (n°1223/2009) forbids the use of laboratory animals for testing.
  • In line with UK, Suisse and European regulation regarding the replacement of laboratory animals
Experience

Experience

Over the last 14 years hundreds of samples have been tested

Our testing technology is adapted to a wide range of products including:

  • Ingredients
  • Mixtures
  • Manufactured products
  • Packaging
  • Water samples
International validation

International validation

Exclusive patent from CNRS and MNHN

  • Listed in OECD Guidance Document 150
  • OECD validation
  • Museum of Natural History Recommended
  • Tests Recommended to be used in ECHA and ESFA Guidance Document
Network

Network

Our aim is to help you with any topic related with endocrine disruption

To address all your needs we have gathered our expertise on endocrine disruptors within a wide network of partners: challenges analysis, strategy evaluation, product portofolio safety.

For 14 years
Laboratoire Watchfrog
helps you to address endocrine disruptors issues.

Our mission is to provide you with data which contributes towards the evaluation of the security of your chemicals, products, packaging and water samples.

In addition to our tests we can help you building a tailor-made evaluation strategy according to your needs and taking into account your specific context, providing you with the most relevant methodology and protocols.

Aperçu test thyroïdien
Thyroid test
(learn more)
Aperçu test androgénique
Androgen test
(learn more)
Aperçu test oestrogénique
Estrogen test
(learn more)

Tests are performed on whole endocrine systems.

Tests are compatible with a wide range of
samples

Cosmetics and health care
Chemicals, biocides and plant protection products
Food industry
Food contact and packaging
Baby care
Water and the environment

Cosmetics and health care

  • Evaluation for regulatory purposes
  • Screening of ingredients and product portfolios
  • Environmental impact of products
  • R&D phase
  • Replacement - ingredient substitution
  • Scientific publications
Ingredients
Mixtures & manufactured products
Packaging

Chemicals, biocides and plant protection products

  • Evaluation for regulatory purposes
  • Screening of ingredients and product portfolios
  • Environmental impact of products
  • R&D phase
  • Replacement - ingredient substitution
  • Scientific publications
New molecules
Compounds and co-formulates
Manufactured products

Food industry

  • Evaluation for regulatory purposes
  • Screening of ingredients and product portfolios
  • Environmental impact of products
  • R&D phase
  • Replacement - ingredient substitution
  • Scientific publications
Ingrédients
Finished products
Food contact

Food contact and packaging

  • Evaluation for regulatory purposes
  • Screening of ingredients and product portfolios
  • Environmental impact of products
  • R&D phase
  • Replacement - ingredient substitution
  • Scientific publications
Food contact materials
Migration solutions
Packaging

Baby care

  • Evaluation for regulatory purposes
  • Screening of ingredients and product portfolios
  • Environmental impact of products
  • R&D phase
  • Replacement - ingredient substitution
  • Scientific publications
Ingrédients
Mixtures & manufactured products
Packaging

Water and the environment

  • Measuring treatment efficiency
  • Environmental impact of effluents
  • Evaluation of bathing water & wetlands
  • Study of drinkable water resources
Waste water
Drinkable water resources
Bathing water & wetlands
Previous

Actualités

Next

We can help you with all topics relating to endocrine disruption thanks to our network of partners

Information
Training
Regulatory surveillance

Information - Training - Regulatory surveillance

  • Legal and regulatory framework
  • Staff awareness
  • General/tailor-made training
  • General/targeted monitoring
Premilinary evaluation
Data mining

Premilinary evaluation - Data mining

  • Preliminary evaluation (context and implications)
  • Analysis of available data
  • Literature search
  • Analysis of the quality of existing data
  • Evaluation of data gaps
  • Implementation of screening/testing strategy
Testing
Interpretation of results

Testing - Interpretation of results

  • Level 1 : OECD evaluation (Biblio, in silico…)
  • Level 2 : OECD testing in vitro
  • Level 3, 4 & 5 : OECD testing in vivo
  • Interpretation of results (Hazard assessment)
  • Mechanism study
Risk assessment based on use by the target population

Risk assessment based on use by the target population

  • Exposure evaluation
  • Analysis of health and safety risks of products
  • Preparation of regulatory dossier
  • Analysis of in-house steps taken
Communication plan
Regulatory compliance
Action plan
Product strategy review

Communication plan - Regulatory compliance - Action plan - Product strategy review

  • Analysis of alerts
  • Ranking of opportunities and risks
  • Review of product strategy
  • Substitution help
  • In-house and external communication plan
  • Language/ Position paper /Crisis management

Member of

AFSSI Green Cross Pôle Dream SETAC Vitagora

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