R&D and collaborative projects
Publications
With the aim of advancing science and regulations globally, our PhDs regularly publish articles, in partnership with industry and other scientists.
Some publications are listed here and are available upon request.
The Xenopus Eleutheroembryo Thyroid Assay (XETA), a New Approach Methodology (NAM) for the regulatory assessment of thyroid activity of chemicals.
Du Pasquier David, Tindall Andrew, Weltje Lennart, Lagadic Laurent, Lemkine Gregory.
Environ Toxicol Chem. 2025
Testing the sensitivity of the medaka Transgenic Eleuthero-embryonic THYroid- Specific assay (TETHYS) to different mechanisms of action.
Elise Pesce, Jessica Benitez-Gonzalez, Andrew J Tindall, Gregory F Lemkine, Barbara
Robin-Duchesne, Laurent M Sachs, David Du Pasquier.
Aquat Toxicol. 2024;276:107081.
Electrochemical degradation of diclofenac generates unexpected thyroidogenic transformation products: Implications for environmental risk assessment.
Rafael Reis, Rebecca Dhawle, Romain Girard, Zacharias Frontistis, Dionissios Mantzavinos, Peter de Witte, Deirdre Cabooter, David Du Pasquier.
J Hazard Mater. 2024; 472:134458.
How the Xenopus eleutheroembryonic thyroid assay compares to the amphibian metamorphosis assay for detecting thyroid active chemicals
David Du Pasquier, Benoît Salinier, Katherine K. Coady, Alan Jones, Oliver Körner, Jessica LaRocca, Gregory Lemkine, Barbara Robin-Duchesne, Lennart Weltje, James R. Wheeler, Laurent Lagadic
Regulatory Toxicology and Pharmacology 149 (2024) 105619
Overlapping action of T3 and T4 during Xenopus laevis development
Alicia Tribondeau, David Du Pasquier, Médine Benchouaia, Corinne Blugeon, Nicolas Buisine and Laurent M. Sachs (2024)
Frontiers in Endocrinology 10.3389/fendo.2024.1360188
Evaluation of the endocrine activity of surface water samples using aquatic eleuthero-embryos—A comparison with in vitro assays
Tindall, A. J., Du Pasquier, D., & Lemkine, G. F. (2023)
Water Environment Research, 95(8), e10911.
A Novel Transgenic Model to Study Thyroid Axis Activity in Early Life Stage Medaka
Elise Pesce, Marion Garde, Muriel Rigolet, Andrew J. Tindall, Gregory F. Lemkine, Lisa A. Baumann, Laurent M. Sachs, and David Du Pasquier
Environmental Science & Technology (2023).
Electrochemical degradation of 17α-ethinylestradiol: Transformation products, degradation pathways and in vivo assessment of estrogenic activity
Rafael Reis, Rebecca Dhawle, David Du Pasquier, Andrew J. Tindall, Zacharias Frontistis, Dionissios Mantzavinos, Peter de Witte, Deirdre Cabooter
Environment International 176 (2023) 107992
Oestrogen reporter transgenic medaka for non-invasive evaluation of aromatase activity
Petra Spirhanzlova, Mathilde Leleu, Anthony Sébillot, Gregory F. Lemkine, Taisen Iguchi, Barbara A. Demeneix, Andrew J. Tindall
Comparative Biochemistry and Physiology, Part C 179 (2016) 64–71
Rapid Fluorescent Detection of (Anti)androgens with spiggin-gfp Medaka
Anthony Sébillot, Pauliina Damdimopoulou, Yukiko Ogino, Petra Spirhanzlova, Shinichi Miyagawa, David Du Pasquier, Nora Mouatassim, Taisen Iguchi, Gregory F. Lemkine, Barbara A. Demeneix and Andrew J. Tindall
Environmental Science & Technology (2014)